Alojzije Brkić, mag. chem.

Research Assistant

Contact
Tel: +385 1 4606 233
Mail: alojzije.brkic[at]chem.pmf.hr

Education
2019. Master of Science in Chemistry, thesis on “Effect of mistranslation on the stability of model proteins in cell extract” under mentorship of prof. dr. sc. Ita Gruić Sovulj and doc. dr. sc. Marko Močibob, Division of Biochemistry, Department of Chemistry, Faculty of Science, University of Zagreb.

2017. Bachelor of Science in Chemistry, Department of Chemistry, Faculty of Science, University of Zagreb.


Bartol Božić, mag. chem.

Research Assistant

Contact
Tel: +385 1 4606 233
Mail: bbozic[at]chem.pmf.hr

Education
2020. Master of Science in Chemistry, thesis on “Kinetic characterization of homologous overexpressed isoleucyl-tRNA-synthetases in Bacillus megaterium” under mentorship of prof. dr. sc. Ita Gruić Sovulj, Division of Biochemistry, Department of Chemistry, Faculty of Science, University of Zagreb.

2018. Bachelor of Science in Chemistry, Department of Chemistry, Faculty of Science, University of Zagreb.


Valentina Ević, mag. chem.

Research Assistant

Contact
Tel: +385 1 4606 234
Mail: vevic[at]chem.pmf.hr

Education
2019. Master of Science in Chemistry, thesis on “Kinetic resolution of fluoroalcohols catalysed by lipases” under mentorship of dr. sc. Maja Majerić Elenkov, Division of Organic Chemistry and Biochemistry, Ruđer Bošković Institute.

2016. Bachelor of Science in Chemistry, Department of Chemistry, Faculty of Science, University of Zagreb.


Marija Pranjić, mag. chem.

Research Assistant

Contact
Tel: +385 1 4606 234
Mail: marija.pranjic[at]chem.pmf.hr

Education
2017. Master of Science in Chemistry, thesis on “Ancestral proteins as thermostable analogues of extant proteins” under mentorship of doc. dr. sc. Marko Močibob, Division of Biochemistry, Department of Chemistry, Faculty of Science, University of Zagreb.

2015. Bachelor of Science in Chemistry, Department of Chemistry, Faculty of Science, University of Zagreb.


Vladimir Zanki, mag. biol. mol.

Research Assistant

Contact
Tel: +385 1 4606 233
Mail: vladimir.zanki[at]chem.pmf.hr

Education
2016. Master of Science in Molecular Biology, thesis on “Analysis of protein interactors of cytosolic seryl-tRNA synthetase from plant Arabidopsis thaliana” under mentorship of doc. dr. sc. Jasmina Rokov-Plavec, Division of Biochemistry, Department of Chemistry, Faculty of Science, University of Zagreb.

2014. Bachelor of Science in Biology, Department of Biology, Faculty of Science, University of Zagreb.

Publications
Importance of protein intrinsic conformational dynamics and transient nature of non-covalent interactions in ligand binding affinity
International Journal of Biological Macromolecules. 192 (2021), 692-700, doi:10.1016/j.ijbiomac.2021.10.045
Mario Kekez; Vladimir Zanki; Ivan Antičević; Jasmina Rokov-Plavec; Aleksandra Maršavelski

Antagonistic and synergistic epigenetic modulation using orthologous CRISPR/dCas9-based modular system
Nucleic Acids Research. 2019, doi:10.1093/nar/gkz709
Goran Josipović; Vanja Tadić; Marija Klasić; Vladimir Zanki; Ivona Bečeheli; Felicia Chung; Akram Ghantous; Toma Keser; Josip Madunić; Maria Bošković; Gordan Lauc; Zdenko Herceg; Aleksandar Vojta; Vlatka Zoldoš

Arabidopsis seryl‐tRNA synthetase: the first crystal structure and novel protein interactor of plant aminoacyl‐tRNA synthetase
The FEBS Journal. 286 (2019), 3; 536-554.
Kekez Mario; Zanki Vladimir; Kekez Ivana; Baranasic Jurica; Hodnik Vesna; Duchene Anne-Marie; Anderluh Gregor; Gruic Sovulj Ita; Matković-Čalogović Dubravka; Weygand Durasevic Ivana; Rokov Plavec Jasmina


dr. sc. Igor Živković

Research Assistant

Contact
Tel: +385 1 4606 234
Mail: izivkovic[at]chem.pmf.hr

Education
2021. PhD degree under mentorship of prof. Ita Gruić Sovulj, Division of Biochemistry, Department of Chemistry, Faculty of Science, University of Zagreb

2016. Master of Science in Chemistry, thesis on “ The mechanism of leucine discrimination in the editing site of leucyl-tRNA synthetase” under mentorship of prof. dr. sc. Ita Gruić-Sovulj and prof. dr. sc. Branimir Bertoša, Division of Biochemistry, Department of Chemistry, Faculty of Science, University of Zagreb.

2014. Bachelor of Science in Chemistry, Department of Chemistry, Faculty of Science, University of Zagreb.

Publications
Mechanism of discrimination of isoleucyl‐tRNA synthetase against non‐proteinogenic α‐amino butyrate and its fluorinated analogues
The FEBS Journal. 2020, doi:/10.1111/febs.15053
Igor Zivkovic; Johann Moschner; Beate Koksch; Ita Gruic Sovulj

On the Mechanism and Origin of Isoleucyl-tRNA Synthetase Editing against Norvaline.
Journal of Molecular Biology. 2019, doi:10.1016/j.jmb.2019.01.029
Bilus Mirna; Semanjski Maja; Mocibob Marko; Zivkovic Igor; Cvetesic Nevena; Tawfik S. Dan; Toth-Petroczy Agnes; Macek Boris; Gruic Sovulj Ita

Kinetic Origin of Substrate Specificity in Post-Transfer Editing by Leucyl-tRNA Synthetase
Journal of Molecular Biology, 430 (2018), 1; 1-16
Dulic Morana; Cvetesic Nevena; Zivkovic Igor; Palencia Andres; Cusack Stephen; Bertosa Branimir; Gruic-Sovulj Ita